Mitochondrial Dna and Cancer
نویسندگان
چکیده
Mitochondrial DNA has been proposed to be involved in carcinogenesis because of high susceptibility to mutations and limited repair mechanisms in comparison to nuclear DNA. In this paper, we review mitochondrial genome instability, relation of mitochondrial DNA mutations with apoptosis and mitochondrial genomic aberrations reported in solid tumors of the thyroid, colorectal, breast, and gastric
منابع مشابه
The Mitochondrial DNA 4977-bp Deletion in Patients with Colorectal Cancer: a Case-control Study in Iran
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